diff --git a/python/pyproject.toml b/python/pyproject.toml
index f7800a932..baf9c287b 100755
--- a/python/pyproject.toml
+++ b/python/pyproject.toml
@@ -96,7 +96,7 @@ diffusion = [
   "st_attn==0.0.7",
   "vsa==0.0.4",
   "runai_model_streamer",
-  "cache-dit==1.1.8"
+  "cache-dit==1.2.0"
 ]
 
 tracing = [
diff --git a/python/sglang/multimodal_gen/configs/sample/sampling_params.py b/python/sglang/multimodal_gen/configs/sample/sampling_params.py
index c478bab77..1f6ccb9ce 100644
--- a/python/sglang/multimodal_gen/configs/sample/sampling_params.py
+++ b/python/sglang/multimodal_gen/configs/sample/sampling_params.py
@@ -463,7 +463,9 @@ class SamplingParams:
                 # Re-raise if it's not a safetensors file issue
                 raise
 
-        user_sampling_params = SamplingParams(*args, **kwargs)
+        user_kwargs = dict(kwargs)
+        user_kwargs.pop("diffusers_kwargs", None)
+        user_sampling_params = SamplingParams(*args, **user_kwargs)
         # TODO: refactor
         sampling_params._merge_with_user_params(user_sampling_params)
         sampling_params._adjust(server_args)
diff --git a/python/sglang/multimodal_gen/docs/attention_backends.md b/python/sglang/multimodal_gen/docs/attention_backends.md
index b5f858137..6e191cfca 100644
--- a/python/sglang/multimodal_gen/docs/attention_backends.md
+++ b/python/sglang/multimodal_gen/docs/attention_backends.md
@@ -8,13 +8,16 @@ Attention backends are defined by `AttentionBackendEnum` (`sglang.multimodal_gen
 
 Backend selection is performed by the shared attention layers (e.g. `LocalAttention` / `USPAttention` / `UlyssesAttention` in `sglang.multimodal_gen.runtime.layers.attention.layer`) and therefore applies to any model component using these layers (e.g. diffusion transformer / DiT and encoders).
 
+When using the diffusers backend, `--attention-backend` is passed through to diffusers'
+`set_attention_backend` (e.g., `flash`, `_flash_3_hub`, `sage`, `xformers`, `native`).
+
 - **CUDA**: prefers FlashAttention (FA3/FA4) when supported; otherwise falls back to PyTorch SDPA.
 - **ROCm**: uses FlashAttention when available; otherwise falls back to PyTorch SDPA.
 - **MPS**: always uses PyTorch SDPA.
 
 ## Backend options
 
-The CLI accepts the lowercase names of `AttentionBackendEnum`. The table below lists the backends implemented by the built-in platforms. `fa3`/`fa4` are accepted as aliases for `fa`.
+For SGLang-native pipelines, the CLI accepts the lowercase names of `AttentionBackendEnum`. The table below lists the backends implemented by the built-in platforms. `fa3`/`fa4` are accepted as aliases for `fa`.
 
 | CLI value | Enum value | Notes |
 |---|---|---|
diff --git a/python/sglang/multimodal_gen/docs/cache/cache_dit.md b/python/sglang/multimodal_gen/docs/cache/cache_dit.md
index 01038b6ca..9e0a0f66a 100644
--- a/python/sglang/multimodal_gen/docs/cache/cache_dit.md
+++ b/python/sglang/multimodal_gen/docs/cache/cache_dit.md
@@ -24,6 +24,72 @@ sglang generate --model-path Qwen/Qwen-Image \
     --prompt "A beautiful sunset over the mountains"
 ```
 
+## Diffusers Backend Configuration
+
+Cache-DiT supports loading acceleration configs from a custom YAML file. For
+diffusers pipelines, pass the YAML/JSON path via `--cache-dit-config`. This
+flow requires cache-dit >= 1.2.0 (`cache_dit.load_configs`).
+
+### Single GPU inference
+
+Define a `config.yaml` file that contains:
+
+```yaml
+cache_config:
+  max_warmup_steps: 8
+  warmup_interval: 2
+  max_cached_steps: -1
+  max_continuous_cached_steps: 2
+  Fn_compute_blocks: 1
+  Bn_compute_blocks: 0
+  residual_diff_threshold: 0.12
+  enable_taylorseer: true
+  taylorseer_order: 1
+```
+
+Then apply the config with:
+
+```bash
+sglang generate --backend diffusers \
+  --model-path Qwen/Qwen-Image \
+  --cache-dit-config config.yaml \
+  --prompt "A beautiful sunset over the mountains"
+```
+
+### Distributed inference
+
+Define a `parallel_config.yaml` file that contains:
+
+```yaml
+cache_config:
+  max_warmup_steps: 8
+  warmup_interval: 2
+  max_cached_steps: -1
+  max_continuous_cached_steps: 2
+  Fn_compute_blocks: 1
+  Bn_compute_blocks: 0
+  residual_diff_threshold: 0.12
+  enable_taylorseer: true
+  taylorseer_order: 1
+parallelism_config:
+  ulysses_size: auto
+  parallel_kwargs:
+    attention_backend: native
+    extra_parallel_modules: ["text_encoder", "vae"]
+```
+
+`ulysses_size: auto` means cache-dit will auto-detect the world_size. Otherwise,
+set it to a specific integer (e.g., `4`).
+
+Then apply the distributed config with:
+
+```bash
+sglang generate --backend diffusers \
+  --model-path Qwen/Qwen-Image \
+  --cache-dit-config parallel_config.yaml \
+  --prompt "A futuristic cityscape at sunset"
+```
+
 ## Advanced Configuration
 
 ### DBCache Parameters
@@ -151,8 +217,8 @@ SGLang Diffusion x Cache-DiT supports almost all models originally supported in
 
 ## Limitations
 
-- **Single GPU only**: Distributed support (TP/SP) is not yet validated; Cache-DiT will be automatically disabled when
-  `world_size > 1`
+- **SGLang-native pipelines**: Distributed support (TP/SP) is not yet validated; Cache-DiT will be automatically
+  disabled when `world_size > 1`.
 - **SCM minimum steps**: SCM requires >= 8 inference steps to be effective
 - **Model support**: Only models registered in Cache-DiT's BlockAdapterRegister are supported
 
diff --git a/python/sglang/multimodal_gen/docs/cli.md b/python/sglang/multimodal_gen/docs/cli.md
index dcd012f75..189afaf3a 100644
--- a/python/sglang/multimodal_gen/docs/cli.md
+++ b/python/sglang/multimodal_gen/docs/cli.md
@@ -21,6 +21,8 @@ The SGLang-diffusion CLI provides a quick way to access the inference pipeline f
 - `--sp-degree {SP_SIZE}`: Sequence parallelism size (typically should match the number of GPUs)
 - `--ulysses-degree {ULYSSES_DEGREE}`: The degree of DeepSpeed-Ulysses-style SP in USP
 - `--ring-degree {RING_DEGREE}`: The degree of ring attention-style SP in USP
+- `--attention-backend {BACKEND}`: Attention backend to use. For SGLang-native pipelines use `fa`, `torch_sdpa`, `sage_attn`, etc. For diffusers pipelines use diffusers backend names like `flash`, `_flash_3_hub`, `sage`, `xformers`.
+- `--cache-dit-config {PATH}`: Path to a Cache-DiT YAML/JSON config (diffusers backend only)
 
 
 ### Sampling Parameters
diff --git a/python/sglang/multimodal_gen/runtime/pipelines/diffusers_pipeline.py b/python/sglang/multimodal_gen/runtime/pipelines/diffusers_pipeline.py
index a962063f2..b408790d7 100644
--- a/python/sglang/multimodal_gen/runtime/pipelines/diffusers_pipeline.py
+++ b/python/sglang/multimodal_gen/runtime/pipelines/diffusers_pipeline.py
@@ -32,6 +32,7 @@ from sglang.multimodal_gen.runtime.pipelines_core.executors.sync_executor import
 )
 from sglang.multimodal_gen.runtime.pipelines_core.schedule_batch import Req
 from sglang.multimodal_gen.runtime.pipelines_core.stages import PipelineStage
+from sglang.multimodal_gen.runtime.platforms import AttentionBackendEnum
 from sglang.multimodal_gen.runtime.server_args import ServerArgs
 from sglang.multimodal_gen.runtime.utils.hf_diffusers_utils import maybe_download_model
 from sglang.multimodal_gen.runtime.utils.logging_utils import init_logger
@@ -410,7 +411,7 @@ class DiffusersPipeline(ComposedPipelineBase):
             load_kwargs["device_map"] = device_map
 
         # Add quantization config if provided (e.g., BitsAndBytesConfig for 4/8-bit)
-        config = getattr(server_args, "pipeline_config", None)
+        config = server_args.pipeline_config
         if config is not None:
             quant_config = getattr(config, "quantization_config", None)
             if quant_config is not None:
@@ -470,12 +471,15 @@ class DiffusersPipeline(ComposedPipelineBase):
         # Apply attention backend if specified
         self._apply_attention_backend(pipe, server_args)
 
+        # Apply cache-dit acceleration if configured
+        pipe = self._apply_cache_dit(pipe, server_args)
+
         logger.info("Loaded diffusers pipeline: %s", pipe.__class__.__name__)
         return pipe
 
     def _apply_vae_optimizations(self, pipe: Any, server_args: ServerArgs) -> None:
         """Apply VAE memory optimizations (tiling, slicing) from pipeline config."""
-        config = getattr(server_args, "pipeline_config", None)
+        config = server_args.pipeline_config
         if config is None:
             return
 
@@ -499,16 +503,30 @@ class DiffusersPipeline(ComposedPipelineBase):
         See: https://huggingface.co/docs/diffusers/main/en/optimization/attention_backends
         Available backends: flash, _flash_3_hub, sage, xformers, native, etc.
         """
-        backend = getattr(server_args, "diffusers_attention_backend", None)
+        backend = server_args.attention_backend
 
         if backend is None:
-            config = getattr(server_args, "pipeline_config", None)
+            config = server_args.pipeline_config
             if config is not None:
                 backend = getattr(config, "diffusers_attention_backend", None)
 
         if backend is None:
             return
 
+        backend = backend.lower()
+        sglang_backends = {e.name.lower() for e in AttentionBackendEnum} | {
+            "fa3",
+            "fa4",
+        }
+        if backend in sglang_backends:
+            logger.debug(
+                "Skipping diffusers attention backend '%s' because it matches a "
+                "SGLang backend name. Use diffusers backend names when running "
+                "the diffusers backend.",
+                backend,
+            )
+            return
+
         for component_name in ["transformer", "unet"]:
             component = getattr(pipe, component_name, None)
             if component is not None and hasattr(component, "set_attention_backend"):
@@ -525,6 +543,44 @@ class DiffusersPipeline(ComposedPipelineBase):
                         e,
                     )
 
+    def _apply_cache_dit(self, pipe: Any, server_args: ServerArgs) -> Any:
+        """Enable cache-dit for diffusers pipeline if configured."""
+        cache_dit_config = server_args.cache_dit_config
+        if not cache_dit_config:
+            return pipe
+
+        try:
+            import cache_dit
+        except ImportError as e:
+            raise RuntimeError(
+                "cache-dit is required for --cache-dit-config. "
+                "Install it with `pip install cache-dit`."
+            ) from e
+
+        if not hasattr(cache_dit, "load_configs"):
+            raise RuntimeError(
+                "cache-dit>=1.2.0 is required for --cache-dit-config. "
+                "Please upgrade cache-dit."
+            )
+
+        try:
+            cache_options = cache_dit.load_configs(cache_dit_config)
+        except Exception as e:
+            raise ValueError(
+                "Failed to load cache-dit config. Provide a YAML/JSON path (or a dict "
+                "supported by cache-dit>=1.2.0)."
+            ) from e
+
+        try:
+            pipe = cache_dit.enable_cache(pipe, **cache_options)
+        except Exception:
+            # cache-dit is an external integration and can raise a variety of errors.
+            logger.exception("Failed to enable cache-dit for diffusers pipeline")
+            raise
+
+        logger.info("Enabled cache-dit for diffusers pipeline")
+        return pipe
+
     def _get_device_map(self, server_args: ServerArgs) -> str | None:
         """
         Determine device_map for pipeline loading.
@@ -540,7 +596,7 @@ class DiffusersPipeline(ComposedPipelineBase):
         dtype = torch.bfloat16 if torch.cuda.is_bf16_supported() else torch.float16
 
         if hasattr(server_args, "pipeline_config") and server_args.pipeline_config:
-            dit_precision = getattr(server_args.pipeline_config, "dit_precision", None)
+            dit_precision = server_args.pipeline_config.dit_precision
             if dit_precision == "fp16":
                 dtype = torch.float16
             elif dit_precision == "bf16":
diff --git a/python/sglang/multimodal_gen/runtime/server_args.py b/python/sglang/multimodal_gen/runtime/server_args.py
index f95c09eff..d2fa12ff6 100644
--- a/python/sglang/multimodal_gen/runtime/server_args.py
+++ b/python/sglang/multimodal_gen/runtime/server_args.py
@@ -235,7 +235,9 @@ class ServerArgs:
 
     # Attention
     attention_backend: str = None
-    diffusers_attention_backend: str = None  # for diffusers backend only
+    cache_dit_config: str | dict[str, Any] | None = (
+        None  # cache-dit config for diffusers
+    )
 
     # Distributed executor backend
     nccl_port: Optional[int] = None
@@ -452,15 +454,25 @@ class ServerArgs:
             "--attention-backend",
             type=str,
             default=None,
-            choices=[e.name.lower() for e in AttentionBackendEnum] + ["fa3", "fa4"],
-            help="The attention backend to use. If not specified, the backend is automatically selected based on hardware and installed packages.",
+            help=(
+                "The attention backend to use. For SGLang-native pipelines, use "
+                "values like fa, torch_sdpa, sage_attn, etc. For diffusers pipelines, "
+                "use diffusers attention backend names such as flash, _flash_3_hub, "
+                "sage, or xformers."
+            ),
         )
         parser.add_argument(
             "--diffusers-attention-backend",
             type=str,
+            dest="attention_backend",
             default=None,
-            help="Attention backend for diffusers pipelines (e.g., flash, _flash_3_hub, sage, xformers). "
-            "See: https://huggingface.co/docs/diffusers/main/en/optimization/attention_backends",
+            help=argparse.SUPPRESS,
+        )
+        parser.add_argument(
+            "--cache-dit-config",
+            type=str,
+            default=ServerArgs.cache_dit_config,
+            help="Path to a Cache-DiT YAML/JSON config. Enables cache-dit for diffusers backend.",
         )
 
         # HuggingFace specific parameters
@@ -999,7 +1011,7 @@ class ServerArgs:
             raise ValueError("pipeline_config is not set in ServerArgs")
 
         self.pipeline_config.check_pipeline_config()
-        if self.attention_backend is None:
+        if self.attention_backend is None and self.backend != Backend.DIFFUSERS:
             self._set_default_attention_backend()
 
         # parallelism